Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation

Figure 4

T regulatory cells can inhibit the immune response by three mechanisms: (a) By competition with effector cells for IL-2. (b) Through cAMP-mediated immunosuppression. (c) By adenosine production via the ectoenzymes CD39 and CD79.

(a)

(b)

(c)