Review Article

Effects of Invariant NKT Cells on Parasite Infections and Hygiene Hypothesis

Table 1

Classifications of NKT cells.

Type IType IINKT-like

Alternative nameiNKTNon-iNKT, vNKT
CD1-dependentYesYesNo
TCR-chainVα14-Jα18 (mice)DiverseDiverse
Vα24-Jα18 (humans)
TCR-chainV8.2, V7, and V2 (mice)DiverseDiverse
V11 (human)
-GalCer responseYesNoNo
Cytokine profileTh1, Th2, and Th17Th1, Th2Th1