Journal of Immunology Research / 2016 / Article / Tab 3

Research Article

Application of a Plug-and-Play Immunogenicity Assay in Cynomolgus Monkey Serum for ADCs at Early Stages of Drug Development

Table 3

Estimation of cut point factor based on different false positive rates (). Cut point factor (CPF) calculated at different false positive rates based on the within monkey variability observed across 4 biotherapeutics. This generic CPF can be used to establish the floating individual cut point signal according to each cynomolgus monkey baseline signal.

Cut point factor


= false positive rate.

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