Research Article

CXCR3, CCR5, and CRTH2 Chemokine Receptor Expression in Lymphocytes Infiltrating Thyroid Nodules with Coincident Hashimoto’s Thyroiditis Obtained by Fine Needle Aspiration Biopsy

Table 1

Basic clinical, biochemical, and ultrasound characteristics of the study participants.

Patients (thyroid nodules with Hashimoto’s thyroiditis)Controls (pure thyroid nodules) value

4660
Median age5858
FT34.60 (4.30–5.08)4.80 (4.60–5.33)n.s.
FT414.80 (13.03–17.70)15.00 (13.85–15.95)n.s.
TSH2.03 (1.07–3.47)1.54 (0.79–2.02)0.023
TgAb108.75 (70.98–144.45)29.3 (18.5–37.1)<0.001
TPOAb5250.6 (146.00–3428.65)36.5 (29.5–49.0)<0.001
Thyroid volume (mL)10.15 (7.00–16.8)15.6 (9.29–21.88)0.030

Expressed as median (lower quartile-upper quartile). FT3, FT4, TSH, TgAb, and TPOAb: serum concentrations of free triiodothyronine (pmol/L), free thyroxine (pmol/L), thyroid stimulating hormone (mIU/L), antibodies to thyroglobulin (kIU/L), and antibodies to thyroid peroxidase (kIU/L).