The Relationship of Cytokines IL-13 and IL-17 with Autoantibodies Profile in Early Rheumatoid Arthritis

Table 4

Diagnostic performance of the investigated parameters.

Parameter	AUC accuracy	Cut-off value	value	Sensitivity (%)	Specificity (%)	Youden index
IL-13	1.000	10.73	<0.0001	100.00	100.00	1.000
IL-17	0.902	9.40	<0.0001	86.67	100.00	0.866
Autoantibodies
IgM-RF	0.981	9.50	<0.0001	94.12	97.06	0.910
Anti-CCP	0.947	12.50	<0.0001	94.44	91.18	0.856
Anti-cL	0.847	7.50	<0.0001	83.33	76.47	0.598
Anti-RA33	0.762	8.50	0.00062	80.00	64.29	0.422
Markers of inflammation
CRP	0.969	8.70	<0.0001	96.67	100.00	0.966
ESR	0.948	20.50	<0.0001	83.33	92.86	0.762