LPS Cooperates with Poly-L-Arginine to Promote IL-6 and IL-8 Release via the JNK Signaling Pathway in NCI-H292 Cells

Figure 2

Synergistic effect of PLA+LPS on JNK signaling in NCI-H292 cells. The expression levels of p-JNK and JNK were measured by western blotting in NCI-H292 cells stimulated with 5 μg/mL PLA, 5 μg/mL LPS, or 5 μg/mL PLA + 5 μg/mL LPS for 60 min; β-actin was used as an internal control. The PLA+LPS group showed a further increased level of p-JNK, which was greater than that of LPS or PLA alone. Significant differences are shown as follows: compared with the control group, , ; compared with PLA+LPS group, .

(a)

(b)