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Journal of Immunology Research
Volume 2016, Article ID 4097642, 12 pages
http://dx.doi.org/10.1155/2016/4097642
Research Article

Early Differentiation of Human CD11c+NK Cells with γδ T Cell Activation Properties Is Promoted by Dialyzable Leukocyte Extracts

1Oncology Research Unit, Oncology Hospital, Mexican Institute for Social Security, Avenida Cuauhtémoc 330, Colonia Doctores, 06720 Mexico City, Mexico
2Department of Immunology, National School of Biological Sciences (ENCB), National Polytechnic Institute (IPN), Carpio y Plan de Ayala s/n, Colonia Santo Tomás, 11340 Mexico City, Mexico
3Immunochemistry Research Unit, Medical Specialties Hospital, Mexican Institute for Social Security, Avenida Cuauhtémoc 330, Colonia Doctores, 06720 Mexico City, Mexico
4Unidad de Desarrollo e Investigación en Bioprocesos (UDIBI), National School of Biological Sciences (ENCB), National Polytechnic Institute (IPN), Carpio y Plan de Ayala s/n, Colonia Santo Tomás, 11340 Mexico City, Mexico
5Unidad de Investigación, Desarrollo e Innovación Médica y Biotecnológica (UDIMEB), National School of Biological Sciences (ENCB), National Polytechnic Institute (IPN), Carpio y Plan de Ayala s/n, Colonia Santo Tomás, 11340 Mexico City, Mexico
6Department of Pharmacology, School of Medicine, National Autonomous University of Mexico, Ciudad Universitaria, 04510 Mexico City, Mexico

Received 26 March 2016; Revised 9 August 2016; Accepted 10 August 2016

Academic Editor: Takami Sato

Copyright © 2016 Dalia Ramírez-Ramírez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. Kobayashi, T. Suda, and K. Takubo, “How hematopoietic stem/progenitors and their niche sense and respond to infectious stress,” Experimental Hematology, vol. 44, no. 2, pp. 92–100, 2016. View at Publisher · View at Google Scholar · View at Scopus
  2. M. T. Baldridge, K. Y. King, and M. A. Goodell, “Inflammatory signals regulate hematopoietic stem cells,” Trends in Immunology, vol. 32, no. 2, pp. 57–65, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. E. Vadillo, E. Dorantes-Acosta, and R. Pelayo, “Regulation of hematopoietic stem/progenitor cell development by inflammation cues,” in Molecular Aspects of Inflammation, L. Pérez-Martínez, G. Pedraza-Alva, and E. F. Osorio, Eds., Res Signpost 37/661 (2), pp. 71–87, 2014. View at Google Scholar
  4. E. Vadillo and R. Pelayo, “Adult NK lineage development in humans is strengthened upon emergency,” Inflammation and Cell Signaling, vol. 1, no. 3, article e269, 2014. View at Publisher · View at Google Scholar
  5. R. S. Welner, R. Pelayo, and P. W. Kincade, “Evolving views on the genealogy of B cells,” Nature Reviews Immunology, vol. 8, no. 2, pp. 95–106, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Yáñez, H. S. Goodridge, D. Gozalbo, and M. L. Gil, “TLRs control hematopoiesis during infection,” European Journal of Immunology, vol. 43, no. 10, pp. 2526–2533, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. Y. Nagai, K. P. Garrett, S. Ohta et al., “Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment,” Immunity, vol. 24, no. 6, pp. 801–812, 2006. View at Publisher · View at Google Scholar · View at Scopus
  8. R. S. Welner, R. Pelayo, Y. Nagai et al., “Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection,” Blood, vol. 112, no. 9, pp. 3753–3761, 2008. View at Publisher · View at Google Scholar · View at Scopus
  9. E. Vadillo, E. Dorantes-Acosta, L. Arriaga-Pizano et al., “Adult, but not neonatal, human lymphoid progenitors respond to TLR9 ligation by producing functional NK-like cells,” Experimental Hematology, vol. 42, no. 7, pp. 562–573, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. E. Vadillo and R. Pelayo, “Toll-like receptors in development and function of the hematopoietic system,” Revista de Investigación Clínica, vol. 64, no. 5, pp. 461–476, 2012. View at Google Scholar · View at Scopus
  11. A. Vilchis-Ordoñez, A. Contreras-Quiroz, E. Vadillo et al., “Bone marrow cells in acute lymphoblastic leukemia create a proinflammatory microenvironment influencing normal hematopoietic differentiation fates,” BioMed Research International, vol. 2015, Article ID 386165, 14 pages, 2015. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Kobayashi, C. I. Kobayashi, A. Nakamura-Ishizu et al., “Bacterial c-di-GMP affects hematopoietic Stem/progenitors and their niches through STING,” Cell Reports, vol. 11, no. 1, pp. 71–84, 2015. View at Publisher · View at Google Scholar · View at Scopus
  13. D. Viza, H. H. Fudenberg, A. Palareti, D. Ablashi, C. De Vinci, and G. Pizza, “Transfer factor: an overlooked potential for the prevention and treatment of infectious diseases,” Folia Biologica, vol. 59, no. 2, pp. 53–67, 2013. View at Google Scholar · View at Scopus
  14. E. Medina-Rivero, G. Merchand-Reyes, L. Pavón et al., “Batch-to-batch reproducibility of Transferon™,” Journal of Pharmaceutical and Biomedical Analysis, vol. 88, pp. 289–294, 2014. View at Publisher · View at Google Scholar · View at Scopus
  15. U. García-Hernández, F. H. Robledo-Ávila, V. D. Álvarez-Jiménez et al., “Dialyzable leukocyte extracts activate TLR-2 on monocytes,” Natural Product Communications, vol. 9, no. 6, pp. 853–856, 2014. View at Google Scholar · View at Scopus
  16. S. Estrada-Parra, A. Nagaya, E. Serrano et al., “Comparative study of transfer factor and acyclovir in the treatment of herpes zoster,” International Journal of Immunopharmacology, vol. 20, no. 10, pp. 521–535, 1998. View at Publisher · View at Google Scholar · View at Scopus
  17. M. O. Ojeda, C. van't Veer, C. B. Fernández-Ortega, M. D. J. Araña Rosainz, and W. A. Buurman, “Dialyzable leukocyte extract differentially regulates the production of TNFα, IL-6, and IL-8 in bacterial component-activated leukocytes and endothelial cells,” Inflammation Research, vol. 54, no. 2, pp. 74–81, 2005. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Robles-Contreras, L. Vizuet, E. Rivera et al., “Down regulation of IL-8 and IL-6 in human limbal epithelial cells cultured with human dialyzable leukocyte extracts,” Revista Alergia Mexico, vol. 58, no. 3, pp. 147–154, 2011. View at Google Scholar · View at Scopus
  19. R. Berrón-Pérez, R. Chávez-Sánchez, I. Estrada-García et al., “Indications, usage, and dosage of the transfer factor, S. Espinosa-Padilla, R. Cortez-Gómez, E. Serrano-Miranda, R. Ondarza-Aguilera, S. M. Pérez-Tapia, B. Pineda Olvera, M. C. Jiménez-Martínez, A. Portugués, A. Rodríguez, L. Cano, P. U. Pacheco, J. Barrientos, R. Chacón- Salinas, J. Serafín, P. Mendez, A. Monges, E. Cervantes and S. Estrada-Parra,” Revista Alergia Mexico, vol. 54, no. 4, pp. 134–139, 2007. View at Google Scholar
  20. R. A. Fabre, S. M. Pérez-Tapia, L. D. Aguilar et al., “Transfer factors as immunotherapy and supplement of chemotherapy in experimental pulmonary tuberculosis,” Clinical and Experimental Immunology, vol. 136, no. 2, pp. 215–223, 2004. View at Publisher · View at Google Scholar
  21. G. Flores Sandoval, J. Gómez Vera, M. Orea Solano et al., “Factor de transferencia como inmunomodulador específico en el tratamiento de la dematitis atópica moderada a severa,” Revista Alergia México, vol. 52, no. 6, pp. 215–220, 2005. View at Google Scholar
  22. N. Salinas-Jazmín, S. Estrada-Parra, M. A. Becerril-García et al., “Herpes murine model as a biological assay to test dialyzable leukocyte extracts activity,” Journal of Immunology Research, vol. 2015, Article ID 146305, 9 pages, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. T. Bryceson, C. Fauriat, J. M. Nunes et al., “Functional analysis of human NK cells by flow cytometry,” Methods in Molecular Biology, vol. 612, pp. 335–352, 2010. View at Publisher · View at Google Scholar
  24. J. P. Di Santo, “Natural killer cells: diversity in search of a niche,” Nature Immunology, vol. 9, no. 5, pp. 473–475, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. A. de Maria, F. Bozzano, C. Cantoni, and L. Moretta, “Revisiting human natural killer cell subset function revealed cytolytic CD56dimCD16+ NK cells as rapid producers of abundant IFN-γ on activation,” Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 2, pp. 728–732, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Della Chiesa, E. Marcenaro, S. Sivori, S. Carlomagno, S. Pesce, and A. Moretta, “Human NK cell response to pathogens,” Seminars in Immunology, vol. 26, no. 2, pp. 152–160, 2014. View at Publisher · View at Google Scholar · View at Scopus
  27. B. M. Burt, G. Plitas, J. A. Stableford et al., “CD11c identifies a subset of murine liver natural killer cells that responds to adenoviral hepatitis,” Journal of Leukocyte Biology, vol. 84, no. 4, pp. 1039–1046, 2008. View at Publisher · View at Google Scholar · View at Scopus
  28. V. G. Pillarisetty, S. C. Katz, J. I. Bleier, A. B. Shah, and R. P. DeMatteo, “Natural killer dendritic cells have both antigen presenting and lytic function and in response to CpG produce IFN-γ via autocrine IL-12,” Journal of Immunology, vol. 174, no. 5, pp. 2612–2618, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. G. Plitas, U. I. Chaudhry, T. P. Kingham, J. R. Raab, and R. P. DeMatteo, “NK dendritic cells are innate immune responders to Listeria monocytogenes infection,” The Journal of Immunology, vol. 178, no. 7, pp. 4411–4416, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. U. I. Chaudhry, G. Plitas, B. M. Burt, T. P. Kingham, J. R. Raab, and R. P. DeMatteo, “NK dendritic cells expanded in IL-15 exhibit antitumor responses in vivo,” Journal of Immunology, vol. 179, no. 7, pp. 4654–4660, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. U. I. Chaudhry, T. P. Kingham, G. Plitas, S. C. Katz, J. R. Raab, and R. P. DeMatteo, “Combined stimulation with interleukin-18 and CpG induces murine natural killer dendritic cells to produce IFN-γ and inhibit tumor growth,” Cancer Research, vol. 66, no. 21, pp. 10497–10504, 2006. View at Publisher · View at Google Scholar · View at Scopus
  32. E. M. L. Chastain, D. R. Getts, and S. D. Miller, “Deficient natural killer dendritic cell responses underlay the induction of Theiler's virus-induced autoimmunity,” mBio, vol. 6, no. 4, Article ID e01175-15, 2015. View at Publisher · View at Google Scholar · View at Scopus
  33. A. L. Blasius, W. Barchet, M. Cella, and M. Colonna, “Development and function of murine B220+CD11c+NK1.1+ cells identify them as a subset of NK cells,” The Journal of Experimental Medicine, vol. 204, no. 11, pp. 2561–2568, 2007. View at Publisher · View at Google Scholar · View at Scopus
  34. C. W. Chan, E. Crafton, H.-N. Fan et al., “Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity,” Nature Medicine, vol. 12, no. 2, pp. 207–213, 2006. View at Publisher · View at Google Scholar · View at Scopus
  35. J. Taieb, N. Chaput, C. Ménard et al., “A novel dendritic cell subset involved in tumor immunosurveillance,” Nature Medicine, vol. 12, no. 2, pp. 214–219, 2006. View at Publisher · View at Google Scholar · View at Scopus
  36. R. S. Welner, R. Pelayo, K. P. Garrett et al., “Interferon-producing killer dendritic cells (IKDCs) arise via a unique differentiation pathway from primitive c-kitHiCD62L+ lymphoid progenitors,” Blood, vol. 109, no. 11, pp. 4825–4931, 2007. View at Publisher · View at Google Scholar
  37. C. H. GeurtsvanKessel, I. M. Bergen, F. Muskens et al., “Both conventional and interferon killer dendritic cells have antigen-presenting capacity during influenza virus infection,” PLoS ONE, vol. 4, no. 9, Article ID e7187, 2009. View at Publisher · View at Google Scholar · View at Scopus
  38. T. Aranami, S. Miyake, and T. Yamamura, “Differential expression of CD11c by peripheral blood NK cells reflects temporal activity of multiple sclerosis,” The Journal of Immunology, vol. 177, no. 8, pp. 5659–5667, 2006. View at Publisher · View at Google Scholar · View at Scopus
  39. T. Nagasawa, “CXCL12/SDF-1 and CXCR4,” Frontiers in Immunology, vol. 6, article 301, 2015. View at Publisher · View at Google Scholar · View at Scopus
  40. J. Purizaca, I. Meza, and R. Pelayo, “Early lymphoid development and microenvironmental cues in B-cell acute lymphoblastic leukemia,” Archives of Medical Research, vol. 43, no. 2, pp. 89–101, 2012. View at Publisher · View at Google Scholar · View at Scopus
  41. M. Noda, Y. Omatsu, T. Sugiyama, S. Oishi, N. Fujii, and T. Nagasawa, “CXCL12-CXCR4 chemokine signaling is essential for NK-cell development in adult mice,” Blood, vol. 117, no. 2, pp. 451–458, 2011. View at Publisher · View at Google Scholar · View at Scopus
  42. W. Li, A. Okuda, H. Yamamoto et al., “Regulation of development of CD56brightCD11c+ NK-Like cells with helper function by IL-18,” PLoS ONE, vol. 8, no. 12, Article ID e82586, 2013. View at Publisher · View at Google Scholar · View at Scopus
  43. J. Tsuda, W. Li, H. Yamanishi et al., “Involvement of CD56brightCD11c+ cells in IL-18-mediated expansion of human γδ T cells,” Journal of Immunology, vol. 186, no. 4, pp. 2003–2012, 2011. View at Google Scholar
  44. J. C. Ribot, A. DeBarros, and B. Silva-Santos, “Searching for ‘signal 2’: costimulation requirements of γδ T cells,” Cellular and Molecular Life Sciences, vol. 68, no. 14, pp. 2345–2355, 2011. View at Publisher · View at Google Scholar · View at Scopus
  45. Y.-L. Wu, Y.-P. Ding, Y. Tanaka et al., “γδ T cells and their potential for immunotherapy,” International Journal of Biological Sciences, vol. 10, no. 2, pp. 119–135, 2014. View at Publisher · View at Google Scholar · View at Scopus
  46. M. Todaro, M. D'Asaro, N. Caccamo et al., “Efficient killing of human colon cancer stem cells by γδ T lymphocytes,” The Journal of Immunology, vol. 182, no. 11, pp. 7287–7296, 2009. View at Publisher · View at Google Scholar · View at Scopus
  47. T. Sugie, K. Murata-Hirai, M. Iwasaki et al., “Zoledronic acid-induced expansion of γδ T cells from early-stage breast cancer patients: effect of IL-18 on helper NK cells,” Cancer Immunology, Immunotherapy, vol. 62, no. 4, pp. 677–687, 2013. View at Publisher · View at Google Scholar · View at Scopus
  48. N. Fujishima, M. Hirokawa, M. Fujishima et al., “Skewed T cell receptor repertoire of Vδ1+γδ T lymphocytes after human allogeneic haematopoietic stem cell transplantation and the potential role for Epstein-Barr virus-infected B cells in clonal restriction,” Clinical & Experimental Immunology, vol. 149, no. 1, pp. 70–79, 2007. View at Publisher · View at Google Scholar · View at Scopus