Cross-reactivity of yeast vaccine immunized mice sera against divergent H5N1 viruses.
HI Titer
VN/1203/04 H5N1
A/duck/Laos/3295/2006 H5N1
A/duck/Human/795/2002 H5N1
Prime
Boost
5 months
Prime
Boost
5 months
Prime
Boost
5 months
i.m.
Saline
2
4
4
4
2
4
EBY100/pYD1
2
4
4
4
4
4
EBY100/pYD1-HA
25.4
128
40.3
16
40.3
32
16
40.3
32
Inactivated H5N1
32
128
40.3
25.4
32
32
25.4
32
16
i.p.
Saline
2
4
2
4
4
4
EBY100/pYD1
4
4
4
8
2
4
EBY100/pYD1-HA
16
32
25.4
16
32
16
16
16
16
Inactivated H5N1
40.3
128
40.3
32
32
16
25.4
32
25.4
Note: HI titers are presented as geometric means. Asterisks indicate statistically significant as compared with that detected in saline and EBY100/pYD1 treated mice ( per group).
