Common Variable Immunodeficiency and Circulating T_FH

Figure 4

Intracellular cytokines after PHA+IL-2 stimulation of PBMC in CVID and N. The percentage of intracellular cytokines ((a) IL-10, (b) IL-21, and (c) IL-4) in permeabilized CD4+ T cells (CXCR5+ and CXCR5−) was determined after 7 days of PHA+IL-2 stimulation in CVID Group I (), Group II (), and N (). Statistical differences are consigned in the graph. White bars represent unstimulated controls.

(a)

(b)

(c)