Evaluation of Multiple Immunoassay Technology Platforms to Select the Anti-Drug Antibody Assay Exhibiting the Most Appropriate Drug and Target Tolerance

Figure 5

Interdonor variability according to the platform used and the treatment applied to the samples. The signals obtained for the 30 donors were normalized in signal/noise values where the noise represents the mean NC signal measured in each method. The dotted line represents the threshold fixed at a signal/noise value equal to 1.25. The individual sera giving a signal/noise above the threshold were identified and the corresponding bars in the graphs were colored grey.

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