Identification of Novel Vaccine Candidates against Campylobacter through Reverse Vaccinology

Table 2

Potential vaccine candidates selected after blast analysis. tblastn analyses were performed for each amino acid sequence against both C. jejuni and C. coli whole genomes available on the NCBI site. The amount and percentage of sharing among the available genomes were determined. A blastp analysis was also performed against the host Gallus gallus. The six candidates eliminated because of poor sharing among Campylobacter strains are shown in italics.

Protein accession	Description	ID	Sharing among C. jejuni strains		Sharing among; C. coli strains		Similarity in Gallus gallus
			N/93	%	N/9	%
YP_001000996.1	Flagellin B	FlaB	77	83	9	100	No
YP_001000997.1	Flagellin A	FlaA	75	81	9	100	No
YP_001001371.1	Flagellar hook protein	FlgE	15	16	8	89	No
YP_001000562.1	Flagellin protein family		93	100	9	100	No
YP_001000248.1	Flagellar capping protein	FliD	38	41	9	100	No
YP_001000204.1	Putative periplasmic protein		2	2	9	100	No
YP_001000654.1	Putative periplasmic protein		2	2	9	100	No
YP_999769.1	Flagellar hook protein	FlgE-1	93	100	9	100	No
YP_001001115.1	Flagellar hook-associated protein	FlgK	93	100	9	100	No
YP_001000153.1	TonB-dependent receptor, putative, degenerate		90	97	9	100	No
YP_001000945.1	N-Acetylmuramoyl-L-alanine amidase		93	100	9	100	No
YP_001001027.1	Serine protease	PEB4	6	6	1	11	No
YP_001000437.1	Putative OMP		89	96	6	67	No
YP_999838.1	Hypothetical protein		93	100	9	100	No
YP_999817.1	Hypothetical protein		92	99	9	100	No
YP_001000383.1	Flagellar basal body L-ring protein	FlgH	93	100	9	100	No
YP_001000935.1	Major OMP	PorA	81	87	9	100	No
YP_001001008.1	Phospholipase A	PldA	92	99	9	100	No
YP_001001257.1	TonB-dependent heme receptor	ChuA	93	100	9	100	No
YP_001000615.1	Hypothetical protein		64	69	9	100	No
YP_001000663.1	Surface-exposed lipoprotein	JlpA	93	100	9	100	No
YP_001000261.1	Hypothetical protein		92	99	9	100	No