Research Article

Urinary Intestinal Fatty Acid-Binding Protein Can Distinguish Necrotizing Enterocolitis from Sepsis in Early Stage of the Disease

Table 2

Diagnostic performance of standard X-ray (gold standard), ultrasound, and serum or urinary I-FABP as analyzed in this study. Imagine methods refer collectively to the X-ray and ultrasound (USG).

NEC × diseaseImagine methodsSerum I-FABP Urinary I-FABP Imagine methods + urinary I-FABP
X-rayUSGNEC versus sepsisNEC versus controlNEC versus sepsisNEC versus control

Sensitivity41%29%38%31%81%81%91%
Specificity100%100%92%100%100%100%100%
Positive predictive value100%100%86%100%100%100%100%
Negative predictive value53%48%55%31%69%67%89%