Effects of Adoptive Transfer of Tolerogenic Dendritic Cells on Allograft Survival in Organ Transplantation Models: An Overview of Systematic Reviews

Figure 2

Mean difference (95% confidence intervals) for Tol-DC infusion versus untreated groups for allografts survival in heart. All studies involved used MHC complete mismatch models either in rats or in mice. In the footnotes, “−” before “DC” means genetic modification and “+” means substances added in the culture medium. If not specialized, DC refers to donor bone borrow DC; when injection time is involved, we take the transplantation day as day 0. i.v.: intravenous; p.v.: portal vein.