Research Article

Serum 25-Hydroxyvitamin D3 and BAFF Levels Are Associated with Disease Activity in Primary Sjogren’s Syndrome

Table 3

Associations of ESSDAI with serological parameters by univariate and multivariate linear regression.

VariateUnivariate analysesMultivariate analyses (backward stepwise)
value value

Age (years)−0.006 ± 0.0160.732−0.036 ± 0.0200.076
ESR (mm/hr)0.017 ± 0.0080.050
CRP (mg/dL)0.320 ± 0.3740.396
25(OH)-D3 (ng/mL)−0.055 ± 0.015<−0.042 ± 0.016
BAFF (pg/mL)0.001 ± 0.0000.001 ± 0.000
β2 microglobulin (mg/L)0.865 ± 0.321

ESSDAI = EULAR Sjogren’s syndrome disease activity index; ESR = erythrocyte sedimentation rate; CRP = C-reactive protein; BAFF = B cell activation of the TNF family; .