Research Article

Serum HMGB1 Serves as a Novel Laboratory Indicator Reflecting Disease Activity and Treatment Response in Ankylosing Spondylitis Patients

Figure 2

Changes in HMGB1 level and disease severity indices during follow-up. The black lines represent above indexes of AS patients treated with anti-TNF-a biologics and the gray lines represent patients treated with SASP and NSAIDs, during follow-up period. indicates ; indicates .
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