Association of Immunosuppression with DR6 Expression during the Development and Progression of Spontaneous Ovarian Cancer in Laying Hen Model

Figure 10

Changes in DR6 expression during ovarian cancer (OVCA) development and progression. Compared with normal ovaries, the intensities of the DR6 expression (arbitrary values expressed as mean ± SEM in 20,000 μm² area of the tissue) were significantly higher in hens with early stage OVCA () and increased further in hens with late stage OVCA (). However, significant differences were not observed in the intensity of DR6 expression among hens with serous, endometrioid, and mucinous OVCA at late stages. Bars with different letters indicate significant differences in DR6 expression.