Association of Immunosuppression with DR6 Expression during the Development and Progression of Spontaneous Ovarian Cancer in Laying Hen Model

Figure 8

IRG1 expression in normal ovaries and ovarian tumors at early and late stages. Intensities of IRG1 are expressed as arbitrary values (mean ± SEM) in 20,000 μm² area of the tissue. Compared with the normal, the intensity of IRG1 expression was significantly greater in hens with early stage OVCA () and increased further in hens with late stage OVCA (). Significant differences were not observed in the intensity of IRG1 expression among hens with serous, endometrioid, and mucinous OVCA at early and late stages. Bars with different letters indicate significant differences in IRG1 expression.