An Introduction to B-Cell Epitope Mapping and In Silico Epitope Prediction

Table 3

List of web available tools for discontinuous/conformational B-cell epitope prediction.

Tool	Source (URL)	Input data	Ref.
DiscoTope	http://www.cbs.dtu.dk/services/DiscoTope-2.0/	PDB ID or PDB file	[22, 71]
BePro (PEPITO)	http://pepito.proteomics.ics.uci.edu/	PDB ID or PDB file	[79]
ElliPro	http://tools.immuneepitope.org/ellipro/	FASTA or Swiss-Prot ID	[83]
SEPPA	http://badd.tongji.edu.cn/seppa/	PDB ID or PDB file	[81]
EPITOPIA	http://epitopia.tau.ac.il/	FASTA/PDB ID or PDB file	[95]
CBTOPE	http://www.imtech.res.in/raghava/cbtope/	FASTA or FASTA file	[85]
EPCES	http://sysbio.unl.edu/EPCES/	PDB ID or PDB file	[96]
EPSVR	http://sysbio.unl.edu/EPSVR/	PDB ID or PDB file	[97]
PEASE	http://www.ofranlab.org/PEASE	Ag PDB ID or PDB file; Ab FASTA or FASTA file	[88]
EpiPred	http://opig.stats.ox.ac.uk/webapps/sabdab-sabpred/EpiPred.php	PDB ID or PDB file	[72]