Review Article

Dengue Fever: Causes, Complications, and Vaccine Strategies

Table 2

Dengue vaccine candidates currently in different phases of clinical trials.

Type of vaccineDeveloperPhase

Chimeric yellow virus dengue vaccine (CYD)Sanofi PasteurLicensed
Intertypic chimera-DENVaxCDC-Inviragen/TakedaIII
Targeted mutagenesis based LAV-TetraVax-DVNIHIII
Cell culture based LAVWRAIR-GSKII
Purified inactivated vaccine-TDENV-PIVWRAIR-GSKI
Recombinant subunit vaccine-V180 Hawaii Biotech, Merck and Co.I
DNA vaccine expressing prM and E proteinNaval Medical Research Centre, WRAIRI