Research Article

Lactobacillus rhamnosus GG Activation of Dendritic Cells and Neutrophils Depends on the Dose and Time of Exposure

Table 2

LGG dose and time of exposure modulated the MFI of DC surface markers.

MarkerGroupControl5 : 110 : 1100 : 1

MHC
class II
DC 2 h1191 ± 102522 ± 22545 ± 942978 ± 245
DC 18 h1303 ± 372066 ± 1542124 ± 291530 ± 3
DC + neutrophils1191 ± 282010 ± 1072352 ± 781946 ± 80

CD40DC 2 h539 ± 1629 ± 1654 ± 1684 ± 6
DC 18 h489 ± 42735 ± 27721 ± 1370 ± 8
DC + neutrophils437 ± 61576 ± 15642 ± 18390 ± 21

CD83DC 2 h465 ± 20417 ± 11554 ± 79452 ± 22
DC 18 h668 ± 20506 ± 33681 ± 7702 ± 12
DC + neutrophils704 ± 34609 ± 61441 ± 54351 ± 3

CD80DC 2 h515 ± 4537 ± 5516 ± 14568 ± 15
DC 18 h513 ± 3544 ± 12535 ± 10478 ± 28
DC + neutrophils476 ± 6613 ± 16553 ± 10478 ± 21

compared to control with no bacteria.
compared to groups treated with 5 : 1 and 10 : 1 LGG, respectively.
Data are presented as the mean ± SEM.