Research Article
Lactobacillus rhamnosus GG Activation of Dendritic Cells and Neutrophils Depends on the Dose and Time of Exposure
Table 2
LGG dose and time of exposure modulated the MFI of DC surface markers.
| Marker | Group | Control | 5 : 1 | 10 : 1 | 100 : 1 |
| MHC class II | DC 2 h | 1191 ± 10 | 2522 ± 2 | 2545 ± 94 | 2978 ± 245 | DC 18 h | 1303 ± 37 | 2066 ± 154 | 2124 ± 29 | 1530 ± 3 | DC + neutrophils | 1191 ± 28 | 2010 ± 107 | 2352 ± 78 | 1946 ± 80 |
| CD40 | DC 2 h | 539 ± 1 | 629 ± 1 | 654 ± 1 | 684 ± 6 | DC 18 h | 489 ± 42 | 735 ± 27 | 721 ± 1 | 370 ± 8 | DC + neutrophils | 437 ± 61 | 576 ± 15 | 642 ± 18 | 390 ± 21 |
| CD83 | DC 2 h | 465 ± 20 | 417 ± 11 | 554 ± 79 | 452 ± 22 | DC 18 h | 668 ± 20 | 506 ± 33 | 681 ± 7 | 702 ± 12 | DC + neutrophils | 704 ± 34 | 609 ± 61 | 441 ± 54 | 351 ± 3 |
| CD80 | DC 2 h | 515 ± 4 | 537 ± 5 | 516 ± 14 | 568 ± 15 | DC 18 h | 513 ± 3 | 544 ± 12 | 535 ± 10 | 478 ± 28 | DC + neutrophils | 476 ± 6 | 613 ± 16 | 553 ± 10 | 478 ± 21 |
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compared to control with no bacteria. compared to groups treated with 5 : 1 and 10 : 1 LGG, respectively. Data are presented as the mean ± SEM.
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