Research Article

Effect of N-Feruloylserotonin and Methotrexate on Severity of Experimental Arthritis and on Messenger RNA Expression of Key Proinflammatory Markers in Liver

Figure 1

(a) Level of IL-1β in plasma in pg/mL measured on day 14. (b) Level of CRP in plasma in μg/mL measured on day 28. (c) 12/15-LOX activity in μkat·mg−1 in liver. CO, control group; AA, adjuvant arthritis group; AA-N-f-5HT, adjuvant arthritis group given N-feruloylserotonin; AA-MTX, adjuvant arthritis group given methotrexate. Results are mean ± SEM; . The symbols and + show significant difference: versus CO, versus AA, and versus AA.
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