Research Article

Upregulation of Soluble HLA-G in Chronic Left Ventricular Systolic Dysfunction

Table 4

Distribution of haplotypes of the 14 bp insertion/deletion polymorphism (Del/Ins) and the +3142 SNP (C/G) in the 3′-untranslated region of the HLA-G gene in relation to left ventricular ejection fraction.

Ejection fractionDelC/DelCDelC/DelGDelC/InsCDelC/InsGDelG/DelGDelG/InsGInsG/InsGTotal

>40%62 (31.2%)15 (7.5%)1 (0.5%)74 (37.2%)1 (0.5%)8 (4.0%)38 (19.1%)199 (100.0%)
<40%20 (32.8%)4 (6.6%)0 (0.0%)23 (37.7%)0 (0.0%)9 (14.8%)5 (8.2%)61 (100.0%)

(Chi-Square test, 10.50, df = 4), for the Chi-Square test DelC/InsG was added to the DelC/DelC group and DelG/DelG was added to the DelG/InsG group.