Overcoming the Constraints of Anti-HIV/CD89 Bispecific Antibodies That Limit Viral Inhibition

Figure 1

Schematic diagram of F240 × 14A8 Bi-Fab construction. The structure of the bispecific single chain antibody (biscFv) is depicted in (a) with the VH as either the green oval (14A8) or blue oval (F240) and the VL as the red oval (14A8) or yellow oval (F240). (b) represents the organization of the Bi-Fab.

(a)

(b)