Research Article

Genetic Polymorphisms of IL17 and Chagas Disease in the South and Southeast of Brazil

Table 3

Genotype frequencies of IL17A rs2275913 in Brazilian patients with LVSD in chronic Chagas cardiomyopathy, stratified according to gender.

GenderIL17A G197AWith
LVSD
(%)
Mild/moderate
LVSD
(%)
Control
(%)

MaleGG23 (45.1)13 (59.1)43 (58.11)
GA24 (47.06)9 (40.9)30 (40.54)
AA4 (7.84)01 (1.35)

FemaleGG23 (45.1)11 (37.93)45 (59.21)
GA22 (43.14)15 (51.72)29 (38.16)
AA6 (11.76) 3 (10.35) 2 (2.63)

LVSD, chronic Chagas cardiomyopathy patients with left ventricular systolic dysfunction; OR, odds ratio; CI, confidence interval.
Data adjusted by age.
Only significant results are showed.
OR = 6.63 and 95% CI = 1.21–36.40; with LVSD versus control.
OR = 7.57 and 95% CI = 1.07–53.40; mild/moderate LVSD versus control.