Role of CD8 Regulatory T Cells versus Tc1 and Tc17 Cells in the Development of Human Graft-versus-Host Disease

Figure 3

Cell viability and anti-inflammatory molecules in healthy donors mobilized with G-CSF. Determination of TGF, IL-10, CD39, CD73, and Ki-67 in peripheral blood CD4⁺ and CD8⁺ cells from a control group () and a group of G-CSF-mobilized donors (). Box plots show population distribution and whiskers denote one standard deviation. A significant increase is observed in the number of CD8⁺IL-10⁺ and CD8+Ki67⁺ cells; the change in CD8⁺CD73⁺ cells is not significant, but a marked tendency to increase is shown (); no changes or tendencies are seen in marker expression in CD4⁺ cells. ; .