Renal Transplant Patients Biopsied for Cause and Tested for C4d, DSA, and IgG Subclasses and C1q: Which Humoral Markers Improve Diagnosis and Outcomes?
Table 6
In depth analysis of DSA and C4d+, C4d focally positive, and C4d− patient groups.
value
95% confidence interval MFI
C4d+ DSA MFI versus C4d− DSA MFI
<0.0001
6,436–16,343
Class I C4d+ DSA MFI versus Class I C4d− DSA MFI
<0.0005
2,473–7,616
Class II C4d+ DSA MFI versus Class II C4d− DSA MFI
<0.0011
3,053–10,652
C4d+ DSA MFI versus C4d focally positive DSA MFI
<0.012
1,718–13,443
Class I C4d+ DSA MFI versus Class I C4d focally positive DSA MFI
<0.0005
2,455–7,634
Class II C4d+ DSA MFI versus Class II C4d focally positive DSA MFI
<0.2
NS
Class I C4d focally positive DSA MFI versus Class I C4d− DSA MFI
<0.4
NS
Class II C4d focally positive DSA MFI versus Class II C4d− DSA MFI
