Research Article

Analysis of Serum Cytokines and Single-Nucleotide Polymorphisms of SOD1, SOD2, and CAT in Erysipelas Patients

Table 6

Association between SNPs and characteristics of patients and erysipelas symptoms.

Gender (n (% genotype))Multiplicity of infection (n (% genotype))Lesion location (n (% genotype))Severity (n (% genotype))Form (n (% genotype))
MaleFemaleRecurrentPrimaryLower limbsFaceUpper limbsLow to midSevereErymanthusBullous

Genotype distribution
SOD1 (G7958A)G/G13 (56.5)34 (72.3)23 (71.9)24 (63.2)42 (72.4)5 (55.6)0 (0.0)41 (67.2)6 (66.7)18 (56.3)29 (76.3)
G/A8 (34.8)11 (23.4)6 (18.8)13 (34.2)13 (22.4)4 (44.4)2 (66.7)16 (26.2)3 (33.3)11 (34.4)8 (21.1)
A/A2 (8.7)2 (4.3)3 (9.4)1 (2.6)3 (5.2)0 (0.0)1 (33.3)4 (6.6)0 (0.0)3 (9.4)1 (2.6)
0.4060.2030.0410.5380.165

Allelic distribution
G347652619714298154766
A1215121519432431710

Genotype distribution
SOD2 (T2734C)C/C6 (26.1)14 (29.2)8 (24.2)12 (31.6)15 (25.4)2 (22.2)3 (100.0)16 (25.8)4 (44.4)16 (48.5)4 (10.5)
C/T14 (60.9)31 (64.6)22 (66.7)23 (60.5)39 (66.1)6 (66.7)0 (0.0)40 (64.5)5 (55.6)16 (48.5)29 (76.3)
T/T3 (13.0)3 (6.3)3 (9.1)3 (7.9)5 (8.5)1 (11.1)0 (0.0)6 (9.7)0 (0.0)1 (3.0)5 (13.2)
0.6440.7890.0900.2760.001

Allelic distribution
C265938476910672134837
T2037282949805251839

Only SOD1 (G7958A) and SOD2 (T2734C) with significant difference showed in some properties of the patients and their symptoms. Observed significance difference () between the location of infection and SOD 1 (G7958A). Significant difference was also found between the form of the infection and SOD2 (T2734C).