Analysis of Serum Cytokines and Single-Nucleotide Polymorphisms of SOD1, SOD2, and CAT in Erysipelas Patients
Table 6
Association between SNPs and characteristics of patients and erysipelas symptoms.
Gender (n (% genotype))
Multiplicity of infection (n (% genotype))
Lesion location (n (% genotype))
Severity (n (% genotype))
Form (n (% genotype))
Male
Female
Recurrent
Primary
Lower limbs
Face
Upper limbs
Low to mid
Severe
Erymanthus
Bullous
Genotype distribution
SOD1 (G7958A)
G/G
13 (56.5)
34 (72.3)
23 (71.9)
24 (63.2)
42 (72.4)
5 (55.6)
0 (0.0)
41 (67.2)
6 (66.7)
18 (56.3)
29 (76.3)
G/A
8 (34.8)
11 (23.4)
6 (18.8)
13 (34.2)
13 (22.4)
4 (44.4)
2 (66.7)
16 (26.2)
3 (33.3)
11 (34.4)
8 (21.1)
A/A
2 (8.7)
2 (4.3)
3 (9.4)
1 (2.6)
3 (5.2)
0 (0.0)
1 (33.3)
4 (6.6)
0 (0.0)
3 (9.4)
1 (2.6)
0.406
0.203
0.041
0.538
0.165
Allelic distribution
G
34
76
52
61
97
14
2
98
15
47
66
A
12
15
12
15
19
4
3
24
3
17
10
Genotype distribution
SOD2 (T2734C)
C/C
6 (26.1)
14 (29.2)
8 (24.2)
12 (31.6)
15 (25.4)
2 (22.2)
3 (100.0)
16 (25.8)
4 (44.4)
16 (48.5)
4 (10.5)
C/T
14 (60.9)
31 (64.6)
22 (66.7)
23 (60.5)
39 (66.1)
6 (66.7)
0 (0.0)
40 (64.5)
5 (55.6)
16 (48.5)
29 (76.3)
T/T
3 (13.0)
3 (6.3)
3 (9.1)
3 (7.9)
5 (8.5)
1 (11.1)
0 (0.0)
6 (9.7)
0 (0.0)
1 (3.0)
5 (13.2)
0.644
0.789
0.090
0.276
0.001
Allelic distribution
C
26
59
38
47
69
10
6
72
13
48
37
T
20
37
28
29
49
8
0
52
5
18
39
Only SOD1 (G7958A) and SOD2 (T2734C) with significant difference showed in some properties of the patients and their symptoms. Observed significance difference () between the location of infection and SOD 1 (G7958A). Significant difference was also found between the form of the infection and SOD2 (T2734C).