Journal of Immunology Research / 2017 / Article / Tab 3

Research Article

Polymorphisms of IL12RB2 May Affect the Natural History of Primary Biliary Cholangitis: A Single Centre Study

Table 3

The IL12RB2 polymorphisms (rs3790567, rs6679356) association with cirrhosis in PBC.

SNPGenotype Cirrhosis ()Fisher exact 
value
OR
No (%)Yes (%)

rs3790567A/G83 (25%)/247 (75%)84 (38%)/138 (62%)0.00110.121.8 [1.3–2.6]
AA12 (7.3%)16 (14.4%)NS3.712.1 [0.9–4.7]
AG59 (35.7%)52 (46.9%)NS3.391.6 [0.9–2.6]
GG94 (57%)43 (38.7%)0.0038.820.5 [0.3–0.8]

rs6679356C/T69 (20.8%)/263 (79.2%)68 (31%)/152 (69%)0.0137.271.7 [1.1–2.5]
CC10 (6%)12 (10.9%)NS2.151.9 [0.8–4.6]
CT49 (29.5%)44 (40%)NS3.251.6 [0.9–2.6]
TT107 (64.5%)54 (49.1%)0.0096.430.5 [0.3–0.9]