Effects of Vitamin B6 Deficiency on the Composition and Functional Potential of T Cell Populations

Table 3

Correlations between plasma PLP level in mice and indices of immune responses.

(a)

	PLP	XA	SI	CD4	CD8	CD4/CD8	IL-2	IL-4	IFN-γ	SOCS-1	T-bet
PLP	1.000
XA	−0.618	1.000
SI	0.284	−0.430	1.000
CD4	−0.684	−0.182	−0.105	1.000
CD8	0.684	0.182	0.105		1.000
CD4/CD8	−0.551	−0.275	−0.163			1.000
IL-2	−0.767		−0.530	0.052	−0.052	−0.037	1.000
IL-4	0.741	0.005	0.311				−0.236	1.000
IFN-γ		−0.513	0.034	−0.666	0.666	−0.552	−0.647	0.706	1.000
SOCS-1	−0.828	0.940	−0.533	0.158	−0.158	0.069		−0.337	−0.712	1.000
T-bet	−0.183	−0.630	0.010	0.866	−0.866	0.919	−0.423	−0.779	−0.217	−0.327	1.000

(b)

	PLP	XA	SI	ΔCD4	ΔCD8	ΔCD4/ΔCD8	ΔIL-2	ΔIL-4	ΔIFN-γ	ΔSOCS-1	ΔT-bet
PLP	1.000
XA	−0.618	1.000
SI	0.284	−0.430	1.000
ΔCD4	−0.905	0.235	−0.221	1.000
ΔCD8	0.905	−0.235	0.221		1.000
ΔCD4/ΔCD8	−0.845	0.139	−0.281			1.000
ΔIL-2	0.391	−0.730	−0.300	−0.024	0.024	0.123	1.000
ΔIL-4	0.670	0.146	0.149	−0.922	0.922		−0.323	1.000
ΔIFN-γ	0.839	−0.180	0.399				−0.166	0.938	1.000
ΔSOCS-1	−0.287	−0.470	−0.256	0.651	−0.651	0.752	0.732	−0.881	−0.758	1.000
ΔT-bet	−0.674	0.787	−0.858	0.478	−0.478	0.466	−0.170	−0.236	−0.552	0.084	1.000

The correlations were calculated as Pearson’s correlation coefficient matrix. CD, cluster of differentiation; IFN-γ, interferon gamma; IL-2, interleukin-2; IL-4, interleukin-4; PLP, pyridoxal 5′-phosphate; SOCS-1, suppressor of cytokine signaling 1; T-bet, T-box transcription factor; XA, xanthurenic acid; Δ means the indictor was detected after ConA stimulation.
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