Research Article

Hydroxychloroquine Use in Lupus Patients during Pregnancy Is Associated with Longer Pregnancy Duration in Preterm Births

Table 1

Patient characteristics of SLE patients.

Total ()Non-HCQ ()HCQ ()

Race (n (%))
 Caucasian56 (89)45 (92)11 (79)
 Black1 (2)1 (2)0 (0)
 Asian6 (10)3 (6)3 (21)
Age at the start of the first registered pregnancy (mean (SD))31.0 (4.1)30.6 (4.0)32.5 (4.3)
Disease duration at the start of the first registered pregnancy6.0 (3.0–10.0)6 (3.5–9.5)4.5 (3–10.8)
Number of registered pregnancies per patient1 (1-2)1 (1-2)2 (1-2)
Antiphospholipid antibodies present7 (11)6 (13)1 (7)
LAC (n (%))
 Negative58 (92)44 (90)14 (100)
 Positive4 (7)4 (9)0 (0)
aCL-IgG (n (%))
 Negative59 (94)45 (92)14 (100)
 Positive3 (54)3 (6)0 (0)
aCL-IgM (n (%))
 Negative61 (97)48 (98)13 (93)
 Positive1 (2)0 (0)1 (7)

SD: standard deviation; IQR: interquartile range. Age and disease duration in years. Data depicted as median (IQR) unless otherwise indicated. Unknown: . Anti-beta2 glycoprotein IgG/IgM was tested in 31 patients in whom it was all negative.