Exemestane Attenuates Hepatic Fibrosis in Rats by Inhibiting Activation of Hepatic Stellate Cells and Promoting the Secretion of Interleukin 10

Figure 1

Effect of EXE administration on CCl₄ and BDL-induced fibrosis in rats. (a) Representative images of liver tissues stained with Sirius Red are shown. Collagen deposition is indicated by the red strands and quantified using ImageJ software of six images. Scale bar 50 μm. (b) Serum ALT and AST levels in the EXE-treated group and control group (10 rats/group). Data were expressed as means ± SD. (c) Collagen deposition was analyzed using Sirius Red staining and quantified six images using ImageJ software. Scale bar 50 μm. (d) Serum ALT and AST levels in the EXE-treated group and control group (10 rats/group). Data were expressed as means ± SD. , .

(a)

(b)

(c)

(d)