Research Article
Exemestane Attenuates Hepatic Fibrosis in Rats by Inhibiting Activation of Hepatic Stellate Cells and Promoting the Secretion of Interleukin 10
Figure 3
EXE inhibits the activation and proliferation of HSCs in vivo. (a) Immunohistochemical staining of α-SMA in liver tissues. Scale bar 50 μm. (b) Quantification of α-SMA-positive area was shown as means ± SD of six images. . (c) Immunohistochemical staining of PCNA in liver tissues. The red arrows indicate PCNA-positive nuclei in myofibroblasts. Scale bar 25 μm. (d) Quantification of PCNA-positive HSCs and % PCNA-positive hepatocytes was shown as means ± SD of six images. .
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