Review Article

HLA Epitopes: The Targets of Monoclonal and Alloantibodies Defined

Figure 5

Epitope 422 shared by A-locus antigens A2, A3, A11, A24, A68, and A69 defined by the aa acid combination 149A + 150A + 151H. One amino acid substitution at position 149 (aa T substituted for aa a) could be the reason that A2 allele is negative while alleles HLA and are positive.