HLA Epitopes: The Targets of Monoclonal and Alloantibodies Defined
Table 4
Cryptic (C) epitopes on dissociated class I HLA antigen—partial list. Complete list in supplemental file.
Epitope number
Dissociated antigen(s)
Epitope site
Epitope number
Dissociated antigen(s)
Epitope sitec
5006
A3002
(152R)
5033
Cw2
(211T)
5007
A31, A33
(73I)
5036
Cw17
(116F) + (143S)
5008
A3401
(63N) + (66K)
5038
Cw6
(9D) + (97W)
5009
A3402
(63N) + (66K) + (156L)
5039
Cw7
(66K) + (99S)
5010
A80
(31S)
5049
A6602
(114Q) + 163E
5027
B8
(9D)
5052
B76
(70N) + 166D
5031
B82
(24S) + (99F)
cAmino acids and their positions on the HLA-dissociated antigens define each epitope. In intact antigens, these amino acids are not exposed at the surface (cryptic).