Research Article

Beneficial Effects of Prebiotic Saccharomyces cerevisiae Mannan on Allergic Asthma Mouse Models

Table 2

A single oral administration of SC-MN increases IL-10 producing cell numbers in naïve mice.

SpecimenGavage feedingImmunospotMean spot sizes

BALSaline163 ± 1610.0052 ± 0.0022
BALSC-MN586 ± 2110.0060 ± 0.006
SplenocytesSaline35 ± 130.0133 ± 0.0064
SplenocytesSC-MN427 ± 2210.0077 ± 0.0009

Results are mean ± SEM (). We observed that administering SC-MN to mice increased the number of IL-10-producing cells in the BAL (). A similar trend was seen for splenocytes from SC-MN-treated mice.