Bacteriophages and Their Immunological Applications against Infectious Threats

Table 3

Summary of phage-encoded endolysins tested in vivo.

Target pathogen	Endolysin	Animal model	References
Acinetobacter baumannii	PlyF307	Bacteraemia	[97]
Bacillus anthracis	PlyG; PlyPH	Sepsis; Peritonitis	[98, 99]
Pseudomonas aeruginosa	LoGT-008 (Artilysin)	Gut decolonization	[100]
Staphylococcus aureus	ClyS; λSa2-E-lyso-SH3b; LysK/CHAPk; LysGH15; MV-L; PhiSH2; Phi11; PlySs2; Ply187AN-KSH3b; SAL-1; Twort; WMY; 80α; 2638A	Nasal decolonization; Bacteraemia; Sepsis; Mastitis; Endophthalmitis	[101–111]
Streptococcus agalactiae	PlyGBS/PlyGBS90–1; PlySK1249	Vaginal decolonization; Oropharynx decolonization; Bacteraemia	[112–114]
Streptococcus pneumonia	Cpl-1; Cpl-771; PAL	Bacteraemia; Sepsis; Endocarditis; Meningitis	[115–120]
Streptococcus pyogenes	PlyC (formerly C1); PlyPy; PlySs2	Oral decolonization; Bacteraemia	[84, 97, 106]