Research Article

Novel Chemokine-Based Immunotoxins for Potent and Selective Targeting of Cytomegalovirus Infected Cells

Table 3

Antiviral activity of the FTPs.

Potency
log IC50   SEMIC50 [nM]

CX3CL1-FTP−9.3 ± 0.360.52
K14E-FTP−8.1 ± 0.098.9
F49A-FTP−7.7 ± 0.0520
F49A-FTP 2n.a.n.a.
F49A-FTP 3n.a.n.a.
F49A-FTP 4n.a.n.a.
F49A-FTP 5−7.5 ± 0.2430
F49A-FTP 6−8.0 ± 0.109.3
F49A-FTP 7−8.6 ± 0.132.6

IC50 value estimated from 3–5 experiments.
IC50 value estimated from 2 experiments.