Elevated Serum Level of HMGB1 in Patients with the Antiphospholipid Syndrome

Figure 1

(a) Western blot analysis of HMGB1 expression in the serum of APS patients, subjects with pregnancy morbidity, and healthy donors. A lysate of Jurkat T cells (total cells) was analysed as a positive control. A representative blot for each group is shown. (b) Scatter plot analysis of HMGB1 expression levels in APS patients (), subjects with pregnancy morbidity (), and in healthy donors (). The data are presented as densitometric units. The horizontal bars indicate the mean. Serum HMGB1 levels from both APS patients and subjects with pregnancy morbidity were compared to healthy donors. . (c) Scatter plot analysis of HMGB1 expression levels in primary APS (PAPS) () and secondary APS (SAPS) patients (). NS: not significant.

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