TMEM187-IRAK1 Polymorphisms Associated with Rheumatoid Arthritis Susceptibility in Tunisian and French Female Populations: Influence of Geographic Origin
Table 6
Association of SNP haplotypes in the TMEM187-IRAK1 region with RA susceptibility.
Chromosome
Populations
Haplotypes
Frequencies
OR (95%CI)
values
Effects
Controls
Cases
X
Tunisian
[ATC]
0.15
0.15
1.00 (0.63–1.59)
0.995
NA
French
0.09
0.19
3.97 (2.57–6.13)
<0.001
Risk
Tunisian
[GCC]
0.14
0.17
1.21 (0.79–1.89)
0.379
NA
French
0.06
0.15
2.39 (1.52–3.77)
<0.001
Risk
Tunisian
[GTT]
0.15
0.18
1.09 (0.70–1.71)
0.692
NA
French
0.04
0.10
2.05 (1.16–3.62)
0.009
Risk
Tunisian
[GTC]
0.57
0.50
0.77 (0.57–1.04)
0.083
NA
French
0.68
0.39
0.23 (0.16–0.33)
<0.001
Protector
Order of SNPs: [rs13397, rs1059703, rs1059702] NA: no association.
