Research Article
IL-1β and IL-6 Are Highly Expressed in RF+IgE+ Systemic Lupus Erythematous Subtype
Table 3
Serum cytokine levels of SLE patients and healthy controls.
| | Cytokines | SLE patients ()
Median (25%–75%) (pg/mL) | Healthy controls ()
Median (25%–75%) (pg/mL) | value |
| | IL-1β | 3.86 (2.52–6.31) | 1.17 (0.65–1.74) | 0.000 | | IL-6 | 29.71 (19.58–50.59) | 16.98 (14.24–20.74) | 0.000 | | IL-8 | 101.19 (40.00–331.36) | 32.12 (23.70–52.27) | 0.000 | | IL-10 | 5.67 (3.95–7.66) | 0.66 (0.55–3.72) | 0.000 | | IL-17 | 107.54 (75.52–165.86) | 90.29 (69.56–116.04) | 0.003 | | IFN-γ | 552.14 (444.69–629.23) | 326.54 (250.89–389.31) | 0.000 | | IP-10 | 7121.35 (1703.35–68843.27) | 931.04 (665.78–1457.07) | 0.000 | | MCP-1 | 73.39 (36.37–106.18) | 57.72 (46.04–78.83) | 0.021 | | MIP-1β | 165.24 (65.91–530.52) | 120.245 (90.69–181.78) | 0.065 |
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Note. The results were not normally distributed and therefore nonparametric statistics and median and interquartile range were used.
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