Impact of Desensitization on Antiviral Immunity in HLA-Sensitized Kidney Transplant Recipients

Figure 5

The levels of CMV-specific CD4+ T cells (CMV-Th) (a) and CD56+ NK cells (CMV-NK) (b) in 16 CMV sero(+) and 4 sero(−) normal individuals and EBV-specific CD4+ T cells (EBV-Th) (c) and CD56+ NK cells (EBV-NK) (d) in 14 EBV sero(+) normal individuals as analyzed by CFC. Each symbol represents the result from one individual. The dotted line describes the positive cutoff level; ≥0.2% for CMV-Th, ≥0.1% for EBV-Th, and ≥0.5% for CMV- and EBV-NK. The PHA (+) control results were also shown in (c) and (d).

(a) CMV-specific CD4+ T cells

(b) CMV-specific CD56+ NK cells

(c) EBV-specific CD4+ T cells

(d) EBV-specific CD56+ NK cells