pVAXhsp65 Vaccination Primes for High IL-10 Production and Decreases Experimental Encephalomyelitis Severity

Figure 2

Effect of previous vaccination with pVAXhsp65 on EAE development. C57BL/6 mice were immunized with 4 pVAXhsp65 doses and then submitted to EAE induction. Kinetics of clinical scores (a), linear regression analysis of clinical scores (b), and body weight variation (c). Data were presented by mean ± SE of 6 mice and are representative of three independent experiments. represents the difference between immunized and control group with EAE. and .

(a)

(b)

(c)