Sustained High Levels of Both Total and High Molecular Weight Adiponectin in Plasma during the Convalescent Phase of Haemorrhagic Fever with Renal Syndrome Are Associated with Disease Severity

Figure 1

Dynamic changes of the total adiponectin (APN) and high molecular weight (HMW) APN levels in the plasma of patients with HFRS. Comparison of (a) total APN and (b) HMW APN levels in the plasma of patients with HFRS over the different stages of the disease and 6 months after discharge from the hospital. Both total APN and HMW APN levels in the plasma of patients with HFRS were generally elevated starting from the onset of fever, gradually continued to elevate during the course of the disease, and recovered to normal levels when assessed 6 months after discharge. The data were obtained from 171 plasma samples of patients with HFRS and from 16 plasma samples of healthy subjects included as normal controls (NC). The Mann–Whitney U test was used to determine the significance of the difference between two groups, and the black lines represent the medians with the corresponding interquartile range. ; ; ; .

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