Cxcl8b and Cxcr2 Regulate Neutrophil Migration through Bloodstream in Zebrafish

Figure 2

Neutrophil migration decreases when Cxcl8a or Cxcl8b are inhibited during severe damage. (a) Diagram showing the quantified neutrophils in two areas. (b) Lateral view of the caudal section of the embryo tail at 1, 2, and 3 hpd in control and morphant embryos. (c) Quantified neutrophils at the damaged area at 1, 2, and 3 hpd. (d) Quantified neutrophils in circulation during homeostasis, after severe damage and in the absence of Cxcl8a or Cxcl8b function. The neutrophils were quantified at 1, 2, and 3 hpd. value < 0.05; value < 0.01; value < 0.001; value < 0.0001.

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