Research Article

Dickkopf-1 Is a Biomarker for Systemic Lupus Erythematosus and Active Lupus Nephritis

Table 3

The abundances of Wnt-3A, FZD-8, and DKK-1 proteins in the sera and urine of patients with SLE.

Serum SLEUrine SLE
Non-LN-SLE ()LN-SLE ()Non-LN-SLE ()LN-SLE ()

Wnt-3A41.55 ± 2.20 (ng/mL)53.54 ± 3.440.004464.43 ± 1.2564.69 ± 1.250.9805
FZD-85.16 ± 0.22 (ng/mL)5.49 ± 0.250.39615.64 ± 0.206.41 ± 0.210.0323
DKK-112.22 ± 0.55 (ng/mL)17.02 ± 0.720.0002.58 ± 0.132.87 ± 0.220.2633

Data represented the mean ± SEM; variance was analyzed by independent-samples -test using GraphPad Prism5. ; ; and .