Th1/Th2 Balance and Th17/Treg-Mediated Immunity in relation to Murine Resistance to Dextran Sulfate-Induced Colitis

Figure 1

Compared to C57BL/6 mice, BALB/c mice are resistant to DSS-induced mucosal damage and development of acute colitis. Weight loss, survival rate, disease activity index (DAI), colon length, macroscopic changes, and H&E staining of the colon (original magnification ×200) are shown. (a) Weight changes following DSS challenge in C57BL/6 and BALB/c mice. (b) Kaplan-Meier survival curves of BALB/c and C57BL/6 mice following exposure to 3.5% DSS in drinking water (). (c) DAI and (d) colon length changes. (e) Macroscopic changes. (f) H&E staining of colon (original magnification ×200). ; .

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