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Journal of Immunology Research
Volume 2017, Article ID 8193932, 16 pages
https://doi.org/10.1155/2017/8193932
Review Article

The Controversial C5a Receptor C5aR2: Its Role in Health and Disease

Core Research Laboratory, The Second Affiliated Hospital, Xi’an Jiaotong University, Xi’an, Shaanxi, China

Correspondence should be addressed to Ke Li; nc.ude.utjx.liam@il.ek

Received 13 March 2017; Accepted 11 May 2017; Published 15 June 2017

Academic Editor: Ethan M. Shevach

Copyright © 2017 Ting Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [10 citations]

The following is the list of published articles that have cited the current article.

  • Saskia C. A. De Jager, Dominique P. V. De Kleijn, Joost P. G. Sluijter, Judith J. De Haan, Lena Bosch, Anouska Borgman, Marissa Bastemeijer, Maike A. D. Brans, Sander M. Van De Weg, and Hamid El Azzouzi, “Complement 5a Receptor deficiency does not influence adverse cardiac remodeling after pressure-overload in mice,” Scientific Reports, vol. 7, no. 1, 2017. View at Publisher · View at Google Scholar
  • Ting Zhang, Malgorzata A. Garstka, and Ke Li, “Corrigendum to “The Controversial C5a Receptor C5aR2: Its Role in Health and Disease”,” Journal of Immunology Research, vol. 2017, pp. 1–1, 2017. View at Publisher · View at Google Scholar
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  • Christian D. Sadik, Yoshishige Miyabe, Tanya Sezin, and Andrew D. Luster, “The critical role of C5a as an initiator of neutrophil-mediated autoimmune inflammation of the joint and skin,” Seminars in Immunology, 2018. View at Publisher · View at Google Scholar
  • Alexander J. T. Wood, Charlotte Summers, Arlette Vassallo, Edwin R. Chilvers, and Andrew Conway-Morris, “C5a anaphylatoxin and its role in critical illness-induced organ dysfunction,” European Journal of Clinical Investigation, 2018. View at Publisher · View at Google Scholar
  • Xaria X. Li, John D. Lee, Claudia Kemper, and Trent M. Woodruff, “The Complement Receptor C5aR2: A Powerful Modulator of Innate and Adaptive Immunity,” The Journal of Immunology, vol. 202, no. 12, pp. 3339–3348, 2019. View at Publisher · View at Google Scholar
  • Songlin Yu, Dan Wang, Lingmin Huang, Yening Zhang, Ruiheng Luo, Dickson Adah, Yiting Tang, Kai Zhao, and Ben Lu, “The complement receptor C5aR2 promotes protein kinase R expression and contributes to NLRP3 inflammasome activation and HMGB1 release from macrophages,” Journal of Biological Chemistry, vol. 294, no. 21, pp. 8384–8394, 2019. View at Publisher · View at Google Scholar
  • Sandra E. Parker, Angela M. Hanton, Stephen N. Stefanou, Peter G. Noakes, Trent M. Woodruff, and John D. Lee, “Revisiting the role of the innate immune complement system in ALS,” Neurobiology of Disease, 2019. View at Publisher · View at Google Scholar
  • Stefan Lüth, Katharina Bröker, Robin Terzenbach, Frank Bentzien, and Werner Dammermann, “Complement factors C3a and C5a mimick a proinflammatory microenvironment and increase HBV IGRA sensitivity 11 Medical and Health Sciences 1107 Immunology,” Journal of Translational Medicine, vol. 17, no. 1, 2019. View at Publisher · View at Google Scholar