Table 3: C5aR2 KO with lipometabolism.

SourceDisease modelProperties of C5aR2Refs

C5aR2 heterozygous mice from Regeneron Pharmaceutics Inc.Physiological metabolism of C5aR2 KO miceStimulates TG synthesis and glucose transport in adipose tissue[106]
Diet induced obesityAnti-inflammation[95, 113]
Partial hepatectomyPromotes liver regeneration[97]
High fat diet-induced insulin resistanceAnti-inflammation, metabolic regulation[112]