Clinical Study

Association of Toll-Like Cell Receptors TLR2 (p.Arg753GLN) and TLR4 (p.Asp299GLY) Polymorphisms with Indicators of General and Local Immunity in Patients with Atopic Dermatitis

Table 2

Serum cytokine profile of patients with atopic dermatitis with different genotypes for the TLR4 receptor polymorphism rs4986790.

Cytokine profileGenotype
A/A ()
“protective”
()
“polymorphic”

INF-γ (pg/mL)12,2
(95% CI 11,7–17,9)
7,9
(95% CI 7,2–8,4)
IL-4 (pg/mL)15,7
(95% CI 14,1–17,6)
20,4
(95% CI 10,8–30,0)
IL-10 (pg/mL)13,8
(95% CI 12,1–15,3)
21,8
(95% CI 16,2–27,4)

t-test, differences are significant: for and for .