Association of Toll-Like Cell Receptors TLR2 (p.Arg753GLN) and TLR4 (p.Asp299GLY) Polymorphisms with Indicators of General and Local Immunity in Patients with Atopic Dermatitis

Table 3

Comparative characteristics of serum cytokine profile in healthy individuals and patients with atopic dermatitis with different polymorphic genotypes.

Cytokine profile	Genotype
	TLR2 (rs5743708)				TLR4 (rs4986790)
	GG		GA		AA		AG
	Atopic; dermatitis,	Healthy,	Atopic dermatitis,	Healthy,	Atopic; dermatitis,	Healthy,	Atopic; dermatitis,	Healthy,
INF-γ (pg/mL)	11,67 ± 3,7	17,1 ± 3,1	7,82 ± 3,7	17,4 ± 2,9	12,2 ± 3,8	17,8 ± 2,8	7,9 ± 4,2	15,0 ± 1,5
IL-4 (pg/mL)	14,63 ± 2,2	14,4 ± 3,2	20,4 ± 3,8	13,7 ± 4,3	15,7 ± 4,1	14,4 ± 3,2	20,4 ± 3,1	15,1 ± 4,5
IL-10 (pg/mL)	13,2 ± 3,6	14,2 ± 5,4	23,9 ± 3,5	14,5 ± 3,3	13,8 ± 3,3	13,8 ± 3,7	21,8 ± 4,2	14,3 ± 3,5

M ± SD, t-test, differences are significant: for and for .